Xeroderma pigmentosum is an autosomal recessive disease . 着色性干皮病是一种常染色体的退行性疾病。
Squamous cell carcinoma in xeroderma pigmentosum : a clinicopathologic study of 4 cases 4例着色干皮病伴发鳞状细胞癌临床病理分析
Cleaver of the university of california at san francisco , for instance , has shown that people with the disease xeroderma pigmentosum , in which melanocytes are destroyed by exposure to the sun , suffer from significantly higher than normal rates of squamous and basal cell carcinomas , which are usually easily treated 这两种癌通常很容易治疗,更能致命的是恶性黑瘤,但却较少见(在皮肤癌患者中只占4 % ) ,而且只有肤色浅的人才容易得。
英文解释
a rare genetic condition characterized by an eruption of exposed skin occurring in childhood and photosensitivity with severe sunburn; inherited as a recessive autosomal trait in which DNA repair processes are defective so they are more likely to chromosome breaks and cancers when exposed to ultraviolet light